Secondary signet-ring cell tumour of the prostate derived from a primary gastric malignancy

• Published in: Clinical & translational oncology Vol. 7; no. 9; pp. 409 - 411
• Main Authors: Cobo Dols, Manuel, Muñoz Gallardo, Santiago, Peláez Angulo, José, Algarra García, Rosa, Fuente Lupiáñez, Carlos, Gil Calle, Silvia, Villar Chamorro, Ester, Montesa Pino, Alvaro, Alcaide García, Julia, Ales Díaz, Inmaculada, Gutiérrez Calderón, Vanesa, Carabante Ocón, Francisco, Benavides Orgaz, Manuel
• Format: Journal Article
• Language: English
• Published: Italy 01.10.2005
• Subjects: Carcinoma, Signet Ring Cell - diagnosis; Carcinoma, Signet Ring Cell - radiotherapy; Carcinoma, Signet Ring Cell - secondary; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Prostatic Neoplasms - diagnosis; Prostatic Neoplasms - radiotherapy; Prostatic Neoplasms - secondary; Stomach Neoplasms - pathology
• ISSN: 1699-048X; 1699-3055
• DOI: 10.1007/BF02716587

Primary signet-ring cell carcinoma of the prostate is infrequent and even more so as secondary spread of this pathologic sub-type to the prostate. We describe the sixth reported case with a diagnosis of a secondary signet-ring cell tumour of the prostate secondary to a gastric cancer. Five years post-gastrectomy to resect signet-ring cell carcinoma, we detected a secondary intra-prostatic spread with urinary tract obstruction. The physical appearance of the tumour cells was similar to that of the previously-resected signet-cell carcinoma of the stomach. There were no metastases in other sites and the patient was treated with radiotherapy. When confronted with intra-prostatic signet-ring cell adenocarcinoma it is necessary to distinguish between primary and secondary aetiology since this would reflect in the choice of treatment and prognosis.