Hypersensitivity to Benzoyl Peroxide in a Cemented Total Knee Arthroplasty
Abstract A small but significant proportion of cemented total knee arthroplasties develop aseptic loosening. Polyethylene debris is unlikely to be the cause in the small subgroup that experiences early loosening. Allergy to polymethylmethacrylate bone cement or its constituents has been reported in...
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Published in | The Journal of arthroplasty Vol. 22; no. 8; pp. 1226 - 1228 |
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Main Authors | , |
Format | Journal Article |
Language | English |
Published |
Elsevier Inc
2007
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Abstract | Abstract A small but significant proportion of cemented total knee arthroplasties develop aseptic loosening. Polyethylene debris is unlikely to be the cause in the small subgroup that experiences early loosening. Allergy to polymethylmethacrylate bone cement or its constituents has been reported in several different industries and in dentistry, dermatology, and joint arthroplasty. Although allergy to polymethylmethacrylate bone cement or its constituents is unusual, the possibility of a systemic inflammatory response and consequent pain and loosening must be considered. We report a case history of a patient who developed a systemic reaction and intractable pain after a total knee arthroplasty who was subsequently shown to be hypersensitive to the benzoyl peroxide component of bone cement. |
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AbstractList | A small but significant proportion of cemented total knee arthroplasties develop aseptic loosening. Polyethylene debris is unlikely to be the cause in the small subgroup that experiences early loosening. Allergy to polymethylmethacrylate bone cement or its constituents has been reported in several different industries and in dentistry, dermatology, and joint arthroplasty. Although allergy to polymethylmethacrylate bone cement or its constituents is unusual, the possibility of a systemic inflammatory response and consequent pain and loosening must be considered. We report a case history of a patient who developed a systemic reaction and intractable pain after a total knee arthroplasty who was subsequently shown to be hypersensitive to the benzoyl peroxide component of bone cement. Abstract A small but significant proportion of cemented total knee arthroplasties develop aseptic loosening. Polyethylene debris is unlikely to be the cause in the small subgroup that experiences early loosening. Allergy to polymethylmethacrylate bone cement or its constituents has been reported in several different industries and in dentistry, dermatology, and joint arthroplasty. Although allergy to polymethylmethacrylate bone cement or its constituents is unusual, the possibility of a systemic inflammatory response and consequent pain and loosening must be considered. We report a case history of a patient who developed a systemic reaction and intractable pain after a total knee arthroplasty who was subsequently shown to be hypersensitive to the benzoyl peroxide component of bone cement. |
Author | Gardiner, Jonathan, FRCS (Tr and Orth) Edwards, Stuart Andrew, FRCS (Tr and Orth) |
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Cites_doi | 10.1034/j.1600-0536.2002.470415.x 10.1302/0301-620X.78B4.0780546 10.1097/01634989-199306000-00005 10.1302/0301-620X.56B4.626 10.1111/j.1600-0536.1979.tb05542.x 10.1007/BF00618442 10.1302/0301-620X.73B1.1991768 10.2106/00004623-199306000-00002 10.1097/01634989-199209000-00006 10.1111/j.1600-0536.1985.tb02581.x 10.1038/sj.bdj.4805466 10.1302/0301-620X.72B2.2312557 |
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References | Haddad, Cobb, Bentley (bib11) 1996; 78-B Kuby (bib15) 1997 Evans, Freeman, Miller (bib7) 1974; 56-B Waterman, Schrik (bib10) 1985; 13 Horowitz, Doty, Lane (bib13) 1993; 75-A Delvin, Watts (bib5) 1984; 157 Forschner, Zuberbier, Worm (bib6) 2002; 47 Lalor, Revell, Gray (bib8) 1991; 73-B Jager, Balda (bib9) 1979; 94 Jones, Hungerford (bib1) 1987; 225 Johnson, Mathias (bib2) 1993; 4 Eskola, Santavirta, Konttinen (bib12) 1990; 72-B Malten, Sewtter (bib4) 1992; 3 Fisher (bib3) 1979; 5 Guin (bib14) 1995 Evans (10.1016/j.arth.2006.10.019_bib7) 1974; 56-B Horowitz (10.1016/j.arth.2006.10.019_bib13) 1993; 75-A Eskola (10.1016/j.arth.2006.10.019_bib12) 1990; 72-B Guin (10.1016/j.arth.2006.10.019_bib14) 1995 Johnson (10.1016/j.arth.2006.10.019_bib2) 1993; 4 Waterman (10.1016/j.arth.2006.10.019_bib10) 1985; 13 Kuby (10.1016/j.arth.2006.10.019_bib15) 1997 Fisher (10.1016/j.arth.2006.10.019_bib3) 1979; 5 Malten (10.1016/j.arth.2006.10.019_bib4) 1992; 3 Lalor (10.1016/j.arth.2006.10.019_bib8) 1991; 73-B Jones (10.1016/j.arth.2006.10.019_bib1) 1987; 225 Forschner (10.1016/j.arth.2006.10.019_bib6) 2002; 47 Jager (10.1016/j.arth.2006.10.019_bib9) 1979; 94 Delvin (10.1016/j.arth.2006.10.019_bib5) 1984; 157 Haddad (10.1016/j.arth.2006.10.019_bib11) 1996; 78-B |
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publication-title: Br Dent J contributor: fullname: Watts – volume: 47 start-page: 241 year: 2002 ident: bib6 article-title: Benzoyl peroxide as a cause of airborne contact dermatitis in an orthopaedic technician publication-title: Contact Dermatitis contributor: fullname: Worm – volume: 5 start-page: 55 year: 1979 ident: bib3 article-title: Paresthesia on the fingers accompanying dermatitis due to methylmethacrylate bone cement publication-title: Contact Dermatitis contributor: fullname: Fisher – volume: 72-B start-page: 212 year: 1990 ident: bib12 article-title: Cementless revision of aggressive granulomatous lesions in hip replacements publication-title: J Bone Joint Surg Br contributor: fullname: Konttinen – volume: 56-B start-page: 626 year: 1974 ident: bib7 article-title: Metal sensitivity as a cause of bone necrosis and loosening of the prosthesis in total joint replacement publication-title: J Bone Joint Surg Br contributor: fullname: Miller – volume: 4 start-page: 90 year: 1993 ident: bib2 article-title: Case report: a dentist with allergic contact dermatitis caused by ethylene glycol dimethacrylate publication-title: Am J Contact Dermat contributor: fullname: Mathias – volume: 78-B start-page: 546 year: 1996 ident: bib11 article-title: Hypersensitivity in aseptic loosening of total hip replacements: the role of constituents of bone cement publication-title: J Bone Joint Surg Br contributor: fullname: Bentley – volume: 75-A start-page: 802 year: 1993 ident: bib13 article-title: Studies of the mechanism by which the mechanical failure of polymethylmethacrylate leads to bone resorption publication-title: J Bone Joint Surg Am contributor: fullname: Lane – year: 1995 ident: 10.1016/j.arth.2006.10.019_bib14 contributor: fullname: Guin – volume: 47 start-page: 241 year: 2002 ident: 10.1016/j.arth.2006.10.019_bib6 article-title: Benzoyl peroxide as a cause of airborne contact dermatitis in an orthopaedic technician publication-title: Contact Dermatitis doi: 10.1034/j.1600-0536.2002.470415.x contributor: fullname: Forschner – volume: 225 start-page: 192 year: 1987 ident: 10.1016/j.arth.2006.10.019_bib1 article-title: Cement disease publication-title: Clin Orthop contributor: fullname: Jones – volume: 78-B start-page: 546 year: 1996 ident: 10.1016/j.arth.2006.10.019_bib11 article-title: Hypersensitivity in aseptic loosening of total hip replacements: the role of constituents of bone cement publication-title: J Bone Joint Surg Br doi: 10.1302/0301-620X.78B4.0780546 contributor: fullname: Haddad – volume: 4 start-page: 90 year: 1993 ident: 10.1016/j.arth.2006.10.019_bib2 article-title: Case report: a dentist with allergic contact dermatitis caused by ethylene glycol dimethacrylate publication-title: Am J Contact Dermat doi: 10.1097/01634989-199306000-00005 contributor: fullname: Johnson – volume: 56-B start-page: 626 year: 1974 ident: 10.1016/j.arth.2006.10.019_bib7 article-title: Metal sensitivity as a cause of bone necrosis and loosening of the prosthesis in total joint replacement publication-title: J Bone Joint Surg Br doi: 10.1302/0301-620X.56B4.626 contributor: fullname: Evans – year: 1997 ident: 10.1016/j.arth.2006.10.019_bib15 contributor: fullname: Kuby – volume: 5 start-page: 55 year: 1979 ident: 10.1016/j.arth.2006.10.019_bib3 article-title: Paresthesia on the fingers accompanying dermatitis due to methylmethacrylate bone cement publication-title: Contact Dermatitis doi: 10.1111/j.1600-0536.1979.tb05542.x contributor: fullname: Fisher – volume: 94 start-page: 175 year: 1979 ident: 10.1016/j.arth.2006.10.019_bib9 article-title: Loosening of a total hip prosthesis at contact allergy due to benzoyl peroxide publication-title: Arch Orthop Trauma Surg doi: 10.1007/BF00618442 contributor: fullname: Jager – volume: 73-B start-page: 25 year: 1991 ident: 10.1016/j.arth.2006.10.019_bib8 article-title: Sensitivity to titanium: a cause of implant failure? publication-title: J Bone Joint Surg Br doi: 10.1302/0301-620X.73B1.1991768 contributor: fullname: Lalor – volume: 75-A start-page: 802 year: 1993 ident: 10.1016/j.arth.2006.10.019_bib13 article-title: Studies of the mechanism by which the mechanical failure of polymethylmethacrylate leads to bone resorption publication-title: J Bone Joint Surg Am doi: 10.2106/00004623-199306000-00002 contributor: fullname: Horowitz – volume: 3 start-page: 142 year: 1992 ident: 10.1016/j.arth.2006.10.019_bib4 article-title: Contact dermatitis from acrylated resins in UV Ebecryl printing inks publication-title: Am J Contact Dermat doi: 10.1097/01634989-199209000-00006 contributor: fullname: Malten – volume: 13 start-page: 294 year: 1985 ident: 10.1016/j.arth.2006.10.019_bib10 article-title: Allergy in hip arthroplasty publication-title: Contact Dermatitis doi: 10.1111/j.1600-0536.1985.tb02581.x contributor: fullname: Waterman – volume: 157 start-page: 272 year: 1984 ident: 10.1016/j.arth.2006.10.019_bib5 article-title: Acrylic “allergy”? 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Snippet | Abstract A small but significant proportion of cemented total knee arthroplasties develop aseptic loosening. Polyethylene debris is unlikely to be the cause in... A small but significant proportion of cemented total knee arthroplasties develop aseptic loosening. Polyethylene debris is unlikely to be the cause in the... |
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SubjectTerms | benzoyl peroxide cement allergy Orthopedics total joint arthroplasty |
Title | Hypersensitivity to Benzoyl Peroxide in a Cemented Total Knee Arthroplasty |
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