Hypersensitivity to Benzoyl Peroxide in a Cemented Total Knee Arthroplasty

Abstract A small but significant proportion of cemented total knee arthroplasties develop aseptic loosening. Polyethylene debris is unlikely to be the cause in the small subgroup that experiences early loosening. Allergy to polymethylmethacrylate bone cement or its constituents has been reported in...

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Bibliographic Details
Published inThe Journal of arthroplasty Vol. 22; no. 8; pp. 1226 - 1228
Main Authors Edwards, Stuart Andrew, FRCS (Tr and Orth), Gardiner, Jonathan, FRCS (Tr and Orth)
Format Journal Article
LanguageEnglish
Published Elsevier Inc 2007
Subjects
benzoyl peroxide
cement allergy
Orthopedics
total joint arthroplasty
cement allergy
benzoyl peroxide
total joint arthroplasty
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Summary:Abstract A small but significant proportion of cemented total knee arthroplasties develop aseptic loosening. Polyethylene debris is unlikely to be the cause in the small subgroup that experiences early loosening. Allergy to polymethylmethacrylate bone cement or its constituents has been reported in several different industries and in dentistry, dermatology, and joint arthroplasty. Although allergy to polymethylmethacrylate bone cement or its constituents is unusual, the possibility of a systemic inflammatory response and consequent pain and loosening must be considered. We report a case history of a patient who developed a systemic reaction and intractable pain after a total knee arthroplasty who was subsequently shown to be hypersensitive to the benzoyl peroxide component of bone cement.
ISSN:0883-5403
1532-8406
DOI:10.1016/j.arth.2006.10.019