Application of brain slice cultures for investigating neuronal sprouting

• Published in: Seibutsu Butsuri Vol. 36; no. 4; pp. 176 - 180
• Main Author: SAKAGUCHI, Takuya
• Format: Journal Article
• Language: Japanese; English
• Published: The Biophysical Society of Japan General Incorporated Association 1996
• Subjects: brain; hippocampus; locus coeruleus; neuron; slice culture; sprouting

Axonal sprouting is a form of morphological plastic change of the neurons. It is proposed to underlie long-term changes in brain function and take place even in mature brain. Electriphysiological analysis revealed that chronic stress and antidepressants induce axonal degeneration and sprouting of lo...