Relationship between silent brain infarction, periventricular hyperintensity and blood pressure

• Published in: Japanese Journal of Stroke Vol. 22; no. 4; pp. 585 - 589
• Main Authors: Kobayashi, Shotai, Yamaguchi, Shuhei, Yamashita, Kazuya, Watanabe, Yuji, Aoyama, Koji, Iijima, Kennich
• Format: Journal Article
• Language: Japanese
• Published: The Japan Stroke Society 2000
• Subjects: blood bressure; hypertension; periventricular hyperintensity; silent brain infarction
• ISSN: 0912-0726; 1883-1923
• DOI: 10.3995/jstroke.22.585

We studied the relationship between silent cerebral infarction (SBI), periventricular hyperintensity (PVH) and blood pressure. Subjects were 1522 neurologically normal adults without history of stroke (mean age, 57.8±8.4 years) who received the brain chech-up from 1988 through 1998. We divided into 8 groups according to JNC-IV in blood pressure at brain check-up. The abnormality of ECG and family history of stroke increased with severity with hypertension. Incidence of SBI was 15.4% and it increased with age. SBI and PVH were related with the severity of blood pres-sure grading, especially with stage 2 or more. SBI was more related with uncontrolled blood pressure at brain check-up than history of hypertension, whereas PVH was motre related with history of hypertension than blood pressure at brain check-up. These results suggent that there is some different underlying mechanism related with blood pressure between SBI and PVH.