A CASE OF IMMUNE HEMOLYTIC ANEMIA DUE TO “AUTO” ANTI-A1 ANTIBODY INDUCED BY GROUP O HOMOGRAFT IN RENAL TRANSPLANTATION RECIPIENT

A case of severe auto-immune hemolytic anemia after a living, ABO-incompatible renal transplantation is reported. The recipient, a 34 years old man, blood group A1, Rh0 (D) positive receieved a renal transplant from father whose blood group O, Rh0(D) positive donor. Cyclosporine, prednisolone and mi...

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Published inJournal of the Japan Society of Blood Transfusion Vol. 36; no. 5; pp. 608 - 613
Main Authors Hayashi, Satoru, Aochi, Hiroshi, Nagamine, Keisuke, Oshida, Machiko, Yamamoto, Kazue, Kurata, Yoshiyuki, Takahara, Shirou, Ishibashi, Michio, Sonoda, Takao
Format Journal Article
LanguageJapanese
Published The Japan Society of Transfusion Medicine and Cell Therapy 1990
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Summary:A case of severe auto-immune hemolytic anemia after a living, ABO-incompatible renal transplantation is reported. The recipient, a 34 years old man, blood group A1, Rh0 (D) positive receieved a renal transplant from father whose blood group O, Rh0(D) positive donor. Cyclosporine, prednisolone and mizoribine were used for immunosuppresion. The recipient devloped severe immune hemolytic anemia within 2 weeks of renal transplantation. The recipient's serum contained anti-A1 IgG autoantibody and anti-B IgG antibody on day 18 post-transplantation. The IgG subclass of these antibodies was IgG3.
ISSN:0546-1448
1883-8383
DOI:10.3925/jjtc1958.36.608