Study for the Removal of Leukocytes from Platelet Products Collected by Apheresises

• Published in: Byōin yakugaku Vol. 14; no. 1; pp. 1 - 6
• Main Authors: TAKAKURA, RIMIKO, TAKAYANAGI, MIYUKI, MAEDA, KAZUKO, ISHIKAWA, YUKO, UEDA, YONEO, GOTO, SHOJI, HIRAI, KOSAKU, FUKUDA, TSUNEO, KONDO, SUMIKO, HASEGAWA, IWAZO
• Format: Journal Article
• Language: Japanese
• Published: Japanese Society of Pharmaceutical Health Care and Sciences 1988
• Subjects: apheresis' PC; centrifugation; concentration of leukocytes; Imugard filter; leukocyte removal; platelet recovery; reservation of platelets' functions
• ISSN: 0389-9098; 2185-9477
• DOI: 10.5649/jjphcs1975.14.1

Since apheresises and blood collection systems were acknowledged by the Ministry of Public Welfare in Japan in April 1986, a lot of plasma or platelet products have been collected from volunteers by these systems. Among these platelet products, platelet rich plasma (PRP) and platelet concentrate (PC) have an apparent weak point which is the contamination of many leukocytes (107-109/bag). Therefore we studied the removal of leukocytes from the apheresis' platelet products by the following two methods and the following results were obtained. 1) The centrifuging method: The recovery of platelets: 78.9%, The removal of leukocytes: 88.4%. 2) The Imugard filter method: The recovery of platelets: 89.0%, The removal of leukocytes: 96.0% or more, Thefunctions of platelets: normal.