Properties of Powder Composite Polyhydroxybutyrate–Chitosan-Calcium Phosphate System

Prepared powder polyhydroxybutyrate – chitosan - calcium phosphate composite system with 10 wt % of biopolymer component can be utilized as biocement which is characterized by the prolonged setting time and achieves wash out resistance after 5 minutes of setting. The origin powder tetracalcium phosp...

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Published inPowder Metallurgy Progress Vol. 17; no. 1; pp. 1 - 9
Main Authors Medvecky, L., Stulajterova, R., Giretova, M., Faberova, M.
Format Journal Article
LanguageEnglish
Published Kosice De Gruyter Open 01.12.2017
De Gruyter Poland
Subjects
Agglomerates
biocement
Biocompatibility
Biomedical materials
Biopolymers
Calcium
calcium phosphate cement
Calcium phosphates
Chitosan
composite
Compressive strength
Deceleration
Hardening rate
Osteoblasts
Particulate composites
Phosphates
Polyhydroxybutyrate
Porosity
Setting (hardening)
Substrates
Tetracalcium phosphate
Toxicity
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Summary:Prepared powder polyhydroxybutyrate – chitosan - calcium phosphate composite system with 10 wt % of biopolymer component can be utilized as biocement which is characterized by the prolonged setting time and achieves wash out resistance after 5 minutes of setting. The origin powder tetracalcium phosphate/nanomonetite agglomerates were coated with the thin layer of biopolymer which decelerates both the transformation rate of calcium phosphates and hardening process of composites. The porosity of hardened composite was around 62% and the compressive strength (8 MPa) was close to trabecular bone. No cytotoxicity of composite resulted from live/dead staining of osteoblasts cultured on substrates.
ISSN:1339-4533
1335-8987
1339-4533
DOI:10.1515/pmp-2017-0001