α1-Adrenoceptor activation: A comparison of 4-(anilinomethyl)imidazoles and 4-(phenoxymethyl)imidazoles to related 2-imidazolines

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Bibliographic Details
Published inBioorganic & medicinal chemistry letters Vol. 12; no. 23; pp. 3449 - 3452
Main Authors HODSON, Stephen J, BIGHAM, Eric C, BISHOP, Michael J, GARRISON, Deanna T, GOBEL, Michael J, IRVING, Paul E, LIACOS, James A, NAVAS, Frank III, SAUSSY, David L, SHERMAN, Bryan W, SPEAKE, Jason D
Format Journal Article
LanguageEnglish
Published Oxford Elsevier 01.12.2002
Subjects
Biological and medical sciences
Catecholaminergic system
Medical sciences
Neuropharmacology
Neurotransmitters. Neurotransmission. Receptors
Pharmacology. Drug treatments
Imidazole derivatives
Agonist
Five membered ring
Ether
Structure activity relation
α1A-adrenergic receptor
Nitrogen heterocycle
Benzamide derivatives
Selectivity
Chemical synthesis
In vitro
Aromatic amine
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ISSN:0960-894X
1464-3405
DOI:10.1016/S0960-894X(02)00753-9