A rare case of Isoniazid-induced SJ syndrome in a secondary care hospital in rural South India-A Case Report

All Antitubercular drugs were discontinued and patient was treated with appropriate drugs but due to the increase in severity of SJ syndrome the patient died within 2 weeks This case report concluded that hypersensitivity reactions can occur with the isoniazid which can be dangerous and life threate...

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Bibliographic Details
Published inResearch journal of pharmacy and technology Vol. 13; no. 2; pp. 758 - 760
Main Authors Deepalakshmi, M, Vikashini, R Anu, Dinesh, R, Anusha, R Jerlin, Dharini, Arun, K.P
Format Journal Article
LanguageEnglish
Published Raipur A&V Publications 01.02.2020
Subjects
Case reports
Dermatology
Drug dosages
Hospitals
Nursing education
Pain
Patients
Pharmacy
Skin
Tuberculosis
India
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Summary:All Antitubercular drugs were discontinued and patient was treated with appropriate drugs but due to the increase in severity of SJ syndrome the patient died within 2 weeks This case report concluded that hypersensitivity reactions can occur with the isoniazid which can be dangerous and life threatening. [...]healthcare professionals should be extra vigilant who prescribe first line Anti TB drugs KEYWORDS: [...]symptoms of prolonged fever, malaise can be noticed which is followed by the appearance of red or purple rashes which will spread all over the body (most common parts are palms, dorsal part of hands, soles and extensor surfaces) and it can become blisters and later it may rupture. [...]healthcare professionals should be extra vigilant who prescribe first line Anti TB drugs and patients should be educated regarding the adverse effects of the drugs which are prescribed to them.
ISSN:0974-3618
0974-360X
0974-306X
DOI:10.5958/0974-360X.2020.00143.2