Relationship between Netrin-1 Levels and Diabetes Mellitus Type 2

• Published in: NeuroQuantology Vol. 19; no. 10; pp. 29 - 33
• Main Authors: Assi, Dr. Mohammed Abdulrazzaq, Hammood, Dr. Hanan Jasim, Attia, Zainab Mahdi
• Format: Journal Article
• Language: English
• Published: Bornova Izmir NeuroQuantology 17.11.2021
• Subjects: Blood; Body size; Cholesterol; Diabetes; Diabetes mellitus; Lipids
• ISSN: 1303-5150; 1303-5150
• DOI: 10.14704/nq.2021.19.10.NQ21153

Objects: The study's purpose was to see if there was a link between netrin.1 and type II diabetes patients. Methodology: The present study carried out on (45) patients affected with diabetes mellitus from (120) persons were examined in the education of Diwaniyah hospital from 6th September to the 4th December 2020. The study includes measurement of the body mass index, fasting blood glucose level, HbA1c, lipid profile and level of netrin-1. Results: Our findings were revealed the netrin-1 level was significantly lower in the diabetes (1205.36±753.09) compared to control group (1477.79±700.26; P < 0.01). Our observations were appeared Significantly higher levels of blood cholesterol, TG, LDL, and VLDL-C and In diabetes individuals, there was a significant drop There was a 0.05 difference in HDL-C levels when compared to healthy controls. Conclusion: These findings indicate that low netrin1 concentration in serum are strongly linked to the occurrence of type II diabetes.