Determinants of glycemic control in type 2 diabetes mellitus in Brazil: A sub-analysis of the longitudinal data from the BrazIian type 1 & 2 diabetes disease registry (BINDER)

• Published in: Primary care diabetes Vol. 16; no. 4; pp. 562 - 567
• Main Authors: Moreira, Rodrigo O., Vianna, André G.D., Ferreira, Graziela C., de Paula, Mauricio A.
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01.08.2022
• Subjects: Antidiabetic agents; Developing countries; Epidemiology; Ype 2 diabetes mellitus type 2; Developing countries; Ype 2 diabetes mellitus type 2; Epidemiology; Antidiabetic agents
• ISSN: 1751-9918; 1878-0210
• DOI: 10.1016/j.pcd.2022.04.003

Data on glycemic control and its determinants among Brazilian patients with type-2 diabetes (DM2) are scarce. The BrazIliaN Type 1 & 2 DiabetEs Disease Registry (BINDER) is a multicenter, longitudinal study, designed to investigate the glycemic control in a real-word scenario. 1142 patients participated in the five visits of the BINDER study between April/2017 and October/2019. For each visit, glycemic control was assessed using the last measure available for HbA1c. Sociodemographic and anthropometric characteristics were also analyzed. At baseline, the median HbA1c level was 7.1% (4.1–15.0%); 259 (31.4%) participants had HbA1c ≤ 6.5% and 396 (48.2%) had HbA1c ≤ 7.0%. Younger age (p = 0.014), low educational level (p = 0.025) and the type of healthcare service (public sector; p = 0.0058) were independently associated with the elevated HbA1c. After 2 years, there were no statistically significant differences in HbA1c median values in relation to baseline. In this sample of DM2 patients, younger age, low educational level and being treated at the public service were associated with worse glycemic control. Over a 2-year follow-up, there was no significant change in the median HbA1c. These findings suggest that strategies are needed to improve glycemic control, especially in those treated in the public service. •In Brazil, only 31% of patients with DM2 had HbA1c ≤ 6.5% and 48.2% had HbA1c ≤ 7.0%.•No significant improvement in median HbA1c was seen in a 2 year follow up.•Younger age, low education and public sector were associated with higher HbA1c levels.