Relationships between anthropometric measurements, leptin and IGF-1 levels in Turkish healthy newborns

• Published in: Journal of clinical and experimental investigations Vol. 6; no. 3; p. 214
• Main Authors: Karakaş, Sacide; Adnan Menderes University, School of Medicine, Department of Anatomy, Aydın, Turkey, Tellioğlu, Ayfer Metin; Adnan Menderes University, School of Medicine, Department of Anatomy, Aydın, Turkey, Dişcigil, Güzel; Adnan Menderes University, School of Medicine, Department of Family Medicine, Aydın, Turkey, Karul, Aslıhan B.; Adnan Menderes University, School of Medicine, Department of Biochemistry, Aydın, Turkey, Türkmen, Münevver; Adnan Menderes University, School of Medicine, Department of Pediatrics, Aydın, Turkey
• Format: Journal Article
• Language: English
• Published: East Sussex Sağlık Araştırmaları Derneği 01.09.2015
• Subjects: Anthropometry, newborn, leptin, insulin-like growth factor 1(IGF-1); antropometri, yenidoğan, leptin, insulin benzeri büyüme faktörü 1(IGF-1)
• ISSN: 1309-8578; 1309-6621; 1309-6621
• DOI: 10.5799/ahinjs.01.2015.03.0521

Amaç: Bu çalışmanın amacı, sağlıklı yenidoğanların antropometrik ölçümlerini yapmak ve ölçümlerin serum leptin ve insulin benzeri büyüme faktörü 1(IGF-1) düzeyleriyle ilişkisini araştırmaktır.Yöntemler: Toplam 113(55 erkek, 58 kız) sağlıklı yenidoğanda, ekstremite uzunlukları, deri kıvrım kalınlığı, vücut çevre ölçümleri uygun yöntemler kullanılarak ölçüldü. Serum leptin ve IGF-1 seviyelerine bakıldı.Bulgular: Antropometrik ölçümlerden vücut kitle indeksi, vücut ağırlığı ve suprailiac deri kıvrım kalınlığı ile serum leptin seviyesi arasında orta düzeyde pozitif korelasyon saptandı (p0.05).Sonuç: Bebeklerin antropometrik ölçümleri gelecekteki büyüme ve gelişme düzeyleri konusunda rehberlik edecektir. Leptin büyüme üzerine etkili bir hormondur Objective: The aim of the present study is to determine anthropometric measurements of a group of healthy newborns and evaluate their association with the serum levels of leptin and insulin-like growth factor 1(IGF-1).Methods: Extremity lengths, skinfold thickness, body circumference measurements of 113 heathy newborns were taken by appropriate methods. Of the total 113 newborns, 55 were male and 58 were female. Serum leptin and IGF-1 levels were measured.Results: Leptin levels had moderately positive correlations with body mass index (BMI), weight and suprailiac skinfold thickness (p<0.05). There was no significant relationship between anthropometric measurements and IGF-1 levels (p>0.05).Conclusion: Anthropometric measurements of newborns will be of guidance for the growth and development of their future life. J Clin Exp Invest 2015; 6 (3): 214-219Key words: Anthropometry, newborn, leptin, insulin-like growth factor 1(IGF-1)