Advances in the use of dexmedetomidine for postoperative cognitive dysfunction

Postoperative cognitive dysfunction, a common neurological complication in the perioperative period, seriously affects patient survival and prognosis. Its high incidence has made the study of postoperative cognitive dysfunction challenging. Whether the clinical application of dexmedetomidine, a pote...

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Bibliographic Details
Published inANESTHESIOLOGY AND PERIOPERATIVE SCIENCE Vol. 2; no. 4; pp. 1 - 9
Main Authors Deng, Meng, Wang, Yuan, Zheng, Beibei
Format Journal Article
LanguageEnglish
Published Singapore Springer Nature Singapore 30.10.2024
Springer
Subjects
Anesthesiology
Cognitive neuroscience
Critical Care Medicine
Dexmedetomidine
Epigenetic mechanisms
Intensive
Medicine
Medicine & Public Health
Neurosciences
Pharmacology/Toxicology
Postoperative cognitive dysfunction
Review Article
Surgery
Epigenetic mechanisms
Cognitive neuroscience
Postoperative cognitive dysfunction
Dexmedetomidine
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Summary:Postoperative cognitive dysfunction, a common neurological complication in the perioperative period, seriously affects patient survival and prognosis. Its high incidence has made the study of postoperative cognitive dysfunction challenging. Whether the clinical application of dexmedetomidine, a potential neuroprotective drug, can reduce the incidence of postoperative cognitive dysfunction is controversial, although several potential mechanisms by which dexmedetomidine improves postoperative cognitive dysfunction have been identified; therefore, this remains an area in need of further exploration.
ISSN:2731-8389
2731-8389
DOI:10.1007/s44254-024-00078-y