Methionine biosynthesis in Saccharomyces cerevisiae. I. Genetical analysis of auxotrophic mutants

In order to analyse how many structural genes are implicated in the specific steps of the biosynthesis of methionine in Sacch. cerevisiae, a hundred mutants were studied by complementation. 21 groups were defined named MET1 to MET25. Neither recombination between independent mutants of the same comp...

Full description

Saved in:
Bibliographic Details
Published inMolecular & general genetics Vol. 139; no. 2; p. 121
Main Authors Masselot, M, De Robichon-Szulmajster, H
Format Journal Article
LanguageEnglish
Published Germany 05.08.1975
Subjects
Genes
Genetic Linkage
Genetics, Microbial
Methionine - biosynthesis
Mutation
Recombination, Genetic
Saccharomyces cerevisiae - metabolism
Online AccessGet more information

Cover

More Information
Summary:In order to analyse how many structural genes are implicated in the specific steps of the biosynthesis of methionine in Sacch. cerevisiae, a hundred mutants were studied by complementation. 21 groups were defined named MET1 to MET25. Neither recombination between independent mutants of the same complementation group nor linkage between different groups was found. Preliminary to biochemical studies, mutants of each complementation group were tested for their capacity to utilize various precursors of methionine.
ISSN:0026-8925
DOI:10.1007/BF00264692