An economical hemoperfusion system to determine in vitro clearances of various poisons with different adsorbents

• Published in: Archives of toxicology Vol. 46; no. 3-4; p. 215
• Main Authors: Okonek, S, Reininghaus, I, Setyadharma, H, Gaudron, P
• Format: Journal Article
• Language: English
• Published: Germany 01.12.1980
• Subjects: Adsorption; Animals; Digitoxin - poisoning; Hemoperfusion - methods; Humans; Kinetics; Methaqualone - poisoning; Methyl Parathion - poisoning; Paraquat - poisoning; Parathion - poisoning; Poisoning - therapy; Poisons - blood; Rats

An economical hemoperfusion system for clearance studies in vitro was developped. It was ascertained, that hemoperfusion using columns which contain 13 g of adsorbent and perfused at a blood flow rate of 1.25 ml/min results in the same relative clearances as when using clinical sized columns contain...