Right Heart Thrombi in Pulmonary Embolism, Association of Pulmonary Embolism with Acute Exacerbations of Chronic Obstructive Pulmonary Disease, and Catheter-directed Therapies for Acute Pulmonary Embolism

The authors did not report the differences between the groups of patients who had an echocardiogram versus those who did not. [...]the prevalence of PE associated with RHT could have been overestimated because the patients who had transthoracic echocardiogram might have preexisting risk factors that...

Full description

Saved in:
Bibliographic Details
Published inAmerican journal of respiratory and critical care medicine Vol. 196; no. 9; pp. 1213 - 1216
Main Authors Dy, Rajany V., Patel, Sumit, Burns, Ken, Mador, M. Jeffery
Format Journal Article
LanguageEnglish
Published United States American Thoracic Society 01.11.2017
Subjects
Blood clots
Catheters
Chronic obstructive pulmonary disease
Clinical trials
Embolisms
Health risk assessment
Heart
Humans
Mortality
Patients
Pulmonary arteries
Pulmonary Disease, Chronic Obstructive
Pulmonary Embolism
Pulmonary embolisms
Thromboembolism
Thrombosis
Ultrasonic imaging
Online AccessGet full text

Cover

More Information
Summary:The authors did not report the differences between the groups of patients who had an echocardiogram versus those who did not. [...]the prevalence of PE associated with RHT could have been overestimated because the patients who had transthoracic echocardiogram might have preexisting risk factors that may have influenced the clinician to perform the test, and the true prevalence is likely lower than 2.6%. Furthermore, results of this study should influence our risk assessment strategy in managing patients with acute PE. Because the presence of RHT increases mortality risk in otherwise low- and intermediate-risk patients with PE, this study should stimulate interest in examining whether additional therapy beyond routine anticoagulation might lead to improved outcomes in this patient population. [...]the studies included had a majority of male subjects, so the results may not be as accurate in female subjects. Risk stratification currently helps guide therapeutic decision-making, but despite this, hospitalized patients with PE have an in-hospital mortality rate varying from 3 to 65% (18-20), depending on clot burden, presence and severity of hemodynamic instability, and patient comorbidities.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 14
ObjectType-Commentary-3
content type line 23
ISSN:1073-449X
1535-4970
1535-4970
DOI:10.1164/rccm.201704-0719RR