Experimental model of haemophilic arthropathy with high pressure haemarthrosis

An experimental model of haemophilic arthropathy was developed in 12 growing dogs by anastomosing the popliteal artery to the joint cavity of the knee to produce haemarthrosis under considerable pressure. The dogs were sacrificed at intervals of one to eight weeks and the morphological and radiologi...

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Bibliographic Details
Published inInternational orthopaedics Vol. 4; no. 1; p. 57
Main Author Sancho, F G
Format Journal Article
LanguageEnglish
Published Germany 01.06.1980
Subjects
Animals
Disease Models, Animal
Dogs
Female
Hemarthrosis - diagnostic imaging
Hemarthrosis - etiology
Hemarthrosis - pathology
Hemophilia A - complications
Knee Joint - diagnostic imaging
Knee Joint - pathology
Knee Joint - surgery
Male
Popliteal Artery - surgery
Pressure
Radiography
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Summary:An experimental model of haemophilic arthropathy was developed in 12 growing dogs by anastomosing the popliteal artery to the joint cavity of the knee to produce haemarthrosis under considerable pressure. The dogs were sacrificed at intervals of one to eight weeks and the morphological and radiological changes found in the specimens mimicked those occurring in haemophilic arthropathy. In some of the animals total destruction of the articular cartilage and subchondral bone occurred. The significance of a high pressure haemarthrosis is discussed in relation to the development of changes found in haemophilic arthropathy.
ISSN:0341-2695
DOI:10.1007/BF00266604