Pregnancy in aplastic anemia treated with fetal liver and bone marrow hemopoietic cells and antithymocyte globulin

This report describes a patient who had severe refractory anemia and thrombocytopenia during her first pregnancy. She had a remission after delivery but two years later aplastic anemia refractory to steroid and splenectomy developed. After treatment with steroids and antithymocyte globulin the patie...

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Bibliographic Details
Published inArchives of gynecology and obstetrics Vol. 251; no. 4; p. 207
Main Authors Pajor, A, Jánossa, M, Kelemen, E
Format Journal Article
LanguageEnglish
Published Germany 01.07.1992
Subjects
Adult
Anemia, Aplastic - therapy
Antilymphocyte Serum - administration & dosage
Bone Marrow Transplantation
Combined Modality Therapy
Female
Fetal Tissue Transplantation
Hematopoietic Stem Cell Transplantation
Humans
Infant, Newborn
Liver Transplantation
Methylprednisolone - administration & dosage
Pregnancy
Pregnancy Complications, Hematologic - therapy
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Summary:This report describes a patient who had severe refractory anemia and thrombocytopenia during her first pregnancy. She had a remission after delivery but two years later aplastic anemia refractory to steroid and splenectomy developed. After treatment with steroids and antithymocyte globulin the patient had repeated infusions of hemopoietic cells derived from fetal liver and bone marrow, leading to a 7-year remission during which time she had a further successful pregnancy. The patient had a relapse one year later.
ISSN:0932-0067
DOI:10.1007/BF02718389