Worldwide method effectiveness of the Today vaginal contraceptive sponge

The Today vaginal contraceptive sponge is made of polyurethane and contains 1 gram of the spermicide nonoxynol-9. Following preclinical and phase I and II clinical trials, extensive worldwide phase III trials were conducted. These multiclinic trials were conducted according to a common protocol with...

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Bibliographic Details
Published inAdvances in contraception Vol. 1; no. 4; p. 305
Main Authors McClure, D A, Edelman, D A
Format Journal Article
LanguageEnglish
Published Netherlands 01.12.1985
Subjects
Adult
Clinical Trials as Topic
Contraceptive Devices, Female
Female
Humans
Nonoxynol
Polyethylene Glycols - administration & dosage
Polyurethanes
Pregnancy
Spermatocidal Agents - administration & dosage
Vagina
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Summary:The Today vaginal contraceptive sponge is made of polyurethane and contains 1 gram of the spermicide nonoxynol-9. Following preclinical and phase I and II clinical trials, extensive worldwide phase III trials were conducted. These multiclinic trials were conducted according to a common protocol with regularly scheduled follow-up visits and examinations. The cumulative first year method effectiveness rate (life table) was 90 per 100 women. The second year rate was 97 per 100 women. No statistically significant difference was found in method failures between nulliparous and parous women. No serious complications occurred in over 1000 women-years of sponge use.
ISSN:0267-4874
DOI:10.1007/BF01849305