A CASE OF ADRENOCORTICAL CARCINOMA AS AN INCIDENTALOMA

A 44-year-old man found to have a giant liver tumor in abdominal ultrasonography and admitted for further examination was suspected of having a right adrenal tumor from CT and angiography. Endocrinological examination showed elevated urine 17-OHCS and 17-KS, so we made a diagnosis of adrenocortical...

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Published inNihon Rinsho Geka Gakkai Zasshi (Journal of Japan Surgical Association) Vol. 65; no. 2; pp. 514 - 518
Main Authors ITO, Yoshitomo, HASEGAWA, Shunji, HOSHI, Shigenori, OHSHIMA, Hideo, KAJIWARA, Shuji, SASAKI, Katsumi
Format Journal Article
LanguageEnglish
Published Japan Surgical Association 2004
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Summary:A 44-year-old man found to have a giant liver tumor in abdominal ultrasonography and admitted for further examination was suspected of having a right adrenal tumor from CT and angiography. Endocrinological examination showed elevated urine 17-OHCS and 17-KS, so we made a diagnosis of adrenocortical carcinoma and conducted surgical resection. Histopathological diagnosis confirmed adrenocortical carcinoma based on nuclear grade IV, atypical mitosis, 5 or more mitotic figures per 50 high-power fields, etc. Metastases occurred to the liver in months 7, 14, and 31 since surgery. In the first 2 recurrences, tumors were resected but in the third, he underwent embolization for multiple metastases. He is current by under managed medical treatment. The prognosis of adrenocortical carcinoma is very poor because cure is almost impossible without surgical resection. Embolization was effective in this case but is not common for adrenocortical carcinoma. More effective adjuvant therapy or treatment are thus required as an alternative to.
ISSN:1345-2843
1882-5133
DOI:10.3919/jjsa.65.514