INVESTIGATION OF SURGICAL TREATMENT FOR MALIGNANT LYMPHOMA OF THE STOMACH BASED ON THE WHO ORGANIZATION CLASSIFICATION

• Published in: Nihon Rinsho Geka Gakkai Zasshi (Journal of Japan Surgical Association) Vol. 65; no. 11; pp. 2839 - 2842
• Main Authors: HACHISUKA, Takashi, YAMADA, Yukishige, NARIKIYO, Michihiro, UENO, Masatou, YORIKI, Ryou, OHHIGASHI, Yuuichirou, MIZUNO, Takashi, NAKAJIMA, Yoshiyuki, ICHIJIMA, Kunihiko
• Format: Journal Article
• Language: English
• Published: Japan Surgical Association 2004
• ISSN: 1345-2843; 1882-5133
• DOI: 10.3919/jjsa.65.2839

We investigated excision specimens from 21 cases of gastric malignant lymphoma undergoing gastric resection until 2001 based on the WHO organization classification, and elucidated clinicopathological features and the validity of surgical excision. There were seven cases of MALT lymphoma, 13 cases of diffuse large B-cell lymphoma (DLBCL), and one case of follicular lymphoma (FL). Patients with MALT lymphoma had good prognosis by surgical excision and postoperative chemotherapy, though one patient experienced securrence. On the other hand, six out of eight patients with DLBCL with Curability A experienced recurrence. The 5-year-survival rates were 71.3% in all the patients, 100% in patients with MALT lymphoma and 52.7% in those with DLBCL, indicating that the WHO organization classification reflected the degree of clinical malignancy. Internal treatment is preferentially selected to avoid the degradation of the QOL by gastrectomy, however further studies to compare the both therapies may be required in terms of long-term prognosis.