Hydrogenation of testosterone sulfate by the Δ4-3-ketosteroid reductase of rat liver microsomes
TPNH 2 is oxidized in the presence of testosterone or testosterone sulfate and a microsomal preparation from the liver of female rats. In the presence of iorganic phosphate, DPNH 2 also acts as a hydrogen donor. Evidence is presented that testosterone sulfate is converted predominantly to the 4,5-di...
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| Published in | Steroids Vol. 5; no. 1; pp. 45 - 56 |
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| Main Authors | , |
| Format | Journal Article |
| Language | English |
| Published |
Elsevier Inc
1965
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| Online Access | Get full text |
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| Summary: | TPNH
2 is oxidized in the presence of testosterone or testosterone sulfate and a microsomal preparation from the liver of female rats. In the presence of iorganic phosphate, DPNH
2 also acts as a hydrogen donor. Evidence is presented that testosterone sulfate is converted predominantly to the 4,5-dihydro derivative, 3-keto-5α-androstane - 17-yl sulfate. |
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| ISSN: | 0039-128X 1878-5867 |
| DOI: | 10.1016/0039-128X(65)90131-5 |