The Role of Human Papilloma Virus in Penile Carcinogenesis and Preneoplastic Lesions

Penile cancer is a rare and devastating disease especially at advanced stages. The etiology of penile cancer is multifactorial with multiple established risk factors including infection with the human papillomavirus (HPV). Approximately 40% of penile cancers are attributable to HPV, although the lit...

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Bibliographic Details
Published inUrologic clinics of North America Vol. 43; no. 4; pp. 419 - 425
Main Authors Diorio, Gregory J., DO, Giuliano, Anna R., PhD
Format Journal Article
LanguageEnglish
Published Elsevier Inc 01.11.2016
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Summary:Penile cancer is a rare and devastating disease especially at advanced stages. The etiology of penile cancer is multifactorial with multiple established risk factors including infection with the human papillomavirus (HPV). Approximately 40% of penile cancers are attributable to HPV, although the literature describing HPV as a prognostic factor is mixed. The pathogenesis of HPV infection as well as vaccination practices may provide valuable therapeutic agents to treat this rare and difficult disease.
ISSN:0094-0143
1558-318X
DOI:10.1016/j.ucl.2016.06.003