AUTOPSY MEMORANDUM (12) A NEONATAL AUTOPSY CASE OF HERPES SIMPLEX VIRAL INFECTION

One autopsy case of a neonate with herpes simplex virus type 1 (HSV-1) is reported. In this case, isolation from skin lesions and typing of the causative virus were performed virologically, and HSV-1 was identified as the causative virus. At autopsy coagulative necrosis was seen in the liver and adr...

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Published inKita Kantō igaku (The Kitakanto Medical Journal) Vol. 41; no. 3; pp. 519 - 524
Main Authors SUGIHARA, SHIRO, HIRATO, JUNKO, HONMA, MANABU, OGAWA, AKIRA, EBARA, HIROYOSHI, KOIZUMI, TAKENOBU, SUZUKI, SHINOBU
Format Journal Article
LanguageEnglish
Published The Kitakanto Medical Society 1991
Subjects
Herpes simplex virus
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ISSN0023-1908
1883-6135
DOI10.2974/kmj1951.41.519

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Summary:One autopsy case of a neonate with herpes simplex virus type 1 (HSV-1) is reported. In this case, isolation from skin lesions and typing of the causative virus were performed virologically, and HSV-1 was identified as the causative virus. At autopsy coagulative necrosis was seen in the liver and adrenal glands. Numerous intranuclear inclusions were found in the vicinity of the necrotic lesions. Immunohistochemical study showed the same result as the virological study. Electron microscopically viral particles were seen in the necrotic tissue of the liver.
ISSN:0023-1908
1883-6135
DOI:10.2974/kmj1951.41.519