RETRACTED: Synthetic triterpenoids, CDDO-Imidazolide and CDDO-Ethyl amide, induce chondrogenesis
This article has been retracted: please see Elsevier Policy on Article Withdrawal (https://www.elsevier.com/about/our-business/policies/article-withdrawal). This article has been retracted at the request of the Editor-in-Chief due to serious problems with image manipulation. The Smad5 blots in Figur...
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| Published in | Osteoarthritis and cartilage Vol. 20; no. 5; pp. 446 - 450 |
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| Main Authors | , , , , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
Elsevier Ltd
01.05.2012
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| Online Access | Get full text |
| ISSN | 1063-4584 1522-9653 |
| DOI | 10.1016/j.joca.2012.01.018 |
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| Abstract | This article has been retracted: please see Elsevier Policy on Article Withdrawal (https://www.elsevier.com/about/our-business/policies/article-withdrawal).
This article has been retracted at the request of the Editor-in-Chief due to serious problems with image manipulation. The Smad5 blots in Figure 1D have been demonstrated to be identical with the β-actin blots from an antecedent publication in Biochemical Journal (Medici D, Potenta S, Kalluri R: Transforming growth factor-β2 promotes Snail-mediated endothelial-mesenchymal transition through convergence of Smad-dependent and Smad-independent signaling. Biochem J. 2011 Aug 1;437(3):515–20. doi: 10.1042/BJ20101500. PMID: 21585337). This has been the subject of a thorough investigation at the home institution of the author who produced the blots, and confirmed by the Editors of OAC. The co-authors of this study, Drs. Suh, Reddi, and Sporn have stated that all data for Table 1 were produced completely independently and they stand by the veracity of all but the offending Figure. The scientific community takes a very strong view on this matter and apologies are offered to readers of the journal that this was not detected previously. |
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| AbstractList | This article has been retracted: please see Elsevier Policy on Article Withdrawal (https://www.elsevier.com/about/our-business/policies/article-withdrawal).
This article has been retracted at the request of the Editor-in-Chief due to serious problems with image manipulation. The Smad5 blots in Figure 1D have been demonstrated to be identical with the β-actin blots from an antecedent publication in Biochemical Journal (Medici D, Potenta S, Kalluri R: Transforming growth factor-β2 promotes Snail-mediated endothelial-mesenchymal transition through convergence of Smad-dependent and Smad-independent signaling. Biochem J. 2011 Aug 1;437(3):515–20. doi: 10.1042/BJ20101500. PMID: 21585337). This has been the subject of a thorough investigation at the home institution of the author who produced the blots, and confirmed by the Editors of OAC. The co-authors of this study, Drs. Suh, Reddi, and Sporn have stated that all data for Table 1 were produced completely independently and they stand by the veracity of all but the offending Figure. The scientific community takes a very strong view on this matter and apologies are offered to readers of the journal that this was not detected previously. |
| Author | Suh, N. Paul, S. Medici, D. Yoon, T. Lee, H.J. Shah, N. Reddi, A.H. Sporn, M.B. Son, A.I. |
| Author_xml | – sequence: 1 givenname: N. surname: Suh fullname: Suh, N. organization: Department of Chemical Biology, Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, Piscataway, NJ 08854, United States – sequence: 2 givenname: S. surname: Paul fullname: Paul, S. organization: Department of Chemical Biology, Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, Piscataway, NJ 08854, United States – sequence: 3 givenname: H.J. surname: Lee fullname: Lee, H.J. organization: Department of Chemical Biology, Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, Piscataway, NJ 08854, United States – sequence: 4 givenname: T. surname: Yoon fullname: Yoon, T. organization: Department of Chemical Biology, Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, Piscataway, NJ 08854, United States – sequence: 5 givenname: N. surname: Shah fullname: Shah, N. organization: Department of Chemical Biology, Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, Piscataway, NJ 08854, United States – sequence: 6 givenname: A.I. surname: Son fullname: Son, A.I. organization: Department of Chemical Biology, Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, Piscataway, NJ 08854, United States – sequence: 7 givenname: A.H. surname: Reddi fullname: Reddi, A.H. organization: Department of Orthopaedic Surgery, University of California at Davis School of Medicine, Sacramento, CA 95817, United States – sequence: 8 givenname: D. surname: Medici fullname: Medici, D. organization: Division of Matrix Biology, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02115, United States – sequence: 9 givenname: M.B. surname: Sporn fullname: Sporn, M.B. email: michael.sporn@dartmouth.edu organization: Department of Pharmacology, Dartmouth Medical School, Hanover, NH 03755, United States |
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| Cites_doi | 10.1056/NEJMoa1105351 10.1016/j.cytogfr.2009.10.010 10.1038/nrc2129 10.1016/S0945-053X(98)90065-8 10.1074/jbc.M709857200 10.1186/ar326 10.1016/j.bcp.2006.04.030 10.1111/j.1432-0436.2003.07109003.x 10.1371/journal.pone.0022862 10.1172/JCI16198 10.1021/np100826q |
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| References | Garrett (10.1016/j.joca.2012.01.018_bib8) 2003; 80 Suh (10.1016/j.joca.2012.01.018_bib5) 2003; 63 Yore (10.1016/j.joca.2012.01.018_bib16) 2011; 6 Roughley (10.1016/j.joca.2012.01.018_bib11) 2001; 3 Hardingham (10.1016/j.joca.2012.01.018_bib14) 2006; 209 Lee (10.1016/j.joca.2012.01.018_bib10) 2006; 72 Garrett (10.1016/j.joca.2012.01.018_bib7) 2003; 111 Pergola (10.1016/j.joca.2012.01.018_bib3) 2011; 365 Liby (10.1016/j.joca.2012.01.018_bib1) 2007; 7 Sporn (10.1016/j.joca.2012.01.018_bib2) 2011; 74 Shinoda (10.1016/j.joca.2012.01.018_bib12) 2008; 283 Schmitt (10.1016/j.joca.2012.01.018_bib13) 2003; 71 Lefebvre (10.1016/j.joca.2012.01.018_bib15) 1998; 16 Song (10.1016/j.joca.2012.01.018_bib6) 2009; 20 Suh (10.1016/j.joca.2012.01.018_bib4) 1999; 59 Medici (10.1016/j.joca.2012.01.018_bib9) 2010; 74 |
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| Title | RETRACTED: Synthetic triterpenoids, CDDO-Imidazolide and CDDO-Ethyl amide, induce chondrogenesis |
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