RETRACTED: Synthetic triterpenoids, CDDO-Imidazolide and CDDO-Ethyl amide, induce chondrogenesis

• Published in: Osteoarthritis and cartilage Vol. 20; no. 5; pp. 446 - 450
• Main Authors: Suh, N., Paul, S., Lee, H.J., Yoon, T., Shah, N., Son, A.I., Reddi, A.H., Medici, D., Sporn, M.B.
• Format: Journal Article
• Language: English
• Published: Elsevier Ltd 01.05.2012
• ISSN: 1063-4584; 1522-9653
• DOI: 10.1016/j.joca.2012.01.018

This article has been retracted: please see Elsevier Policy on Article Withdrawal (https://www.elsevier.com/about/our-business/policies/article-withdrawal). This article has been retracted at the request of the Editor-in-Chief due to serious problems with image manipulation. The Smad5 blots in Figure 1D have been demonstrated to be identical with the β-actin blots from an antecedent publication in Biochemical Journal (Medici D, Potenta S, Kalluri R: Transforming growth factor-β2 promotes Snail-mediated endothelial-mesenchymal transition through convergence of Smad-dependent and Smad-independent signaling. Biochem J. 2011 Aug 1;437(3):515–20. doi: 10.1042/BJ20101500. PMID: 21585337). This has been the subject of a thorough investigation at the home institution of the author who produced the blots, and confirmed by the Editors of OAC. The co-authors of this study, Drs. Suh, Reddi, and Sporn have stated that all data for Table 1 were produced completely independently and they stand by the veracity of all but the offending Figure. The scientific community takes a very strong view on this matter and apologies are offered to readers of the journal that this was not detected previously.