A Study of Lipid Profile in Patients with Type -2 Diabetes Mellitus

• Published in: MRIMS journal of health sciences Vol. 1; no. 1; pp. 23 - 26
• Main Authors: Kandula, Ramu, Shegokar, VinayakE
• Format: Journal Article
• Language: English
• Published: Wolters Kluwer Medknow Publications 01.07.2013
• Subjects: lipid profile; NCEP guidelines; triglycerides
• ISSN: 2321-7006; 2321-7294
• DOI: 10.4103/2321-7006.301931

Background: It is clear from the population based studies that type-2 diabetes generally is associated with a 50% to 100% elevation in the plasma levels of total and VLDL triglycerides. Objective: To find the pattern of Dyslipidemia in type-2 diabetics in comparison with non diabetic individuals. Methods: A case control study was conducted. Hundred type-2 diabetes mellitus patients were taken as cases and hundred age and sex matched non diabetic individuals were taken as controls. The labeling of dyslipidemia was based on NCEP guidelines. Results: Dyslipidemia was present in 86% of diabetic patients. LDL dyslipidemia was observed in 64%, HDL dyslipidemia in 71% and hypertriglyceridemia in 47% and hypercholesterolemia in 41% of diabetic patients. The total cholesterol, triglycerides, LDL-C are significantly elevated in diabetics when compared to control (p=0.003, p<0.0001, p<0.0001) while HDL-C values are significantly lowered in diabetics when compared to Non-diabetics (p=0.007). Conclusion: The alteration of lipid metabolism of type-2 diabetics has raised a serious medical concern with respect to vascular complications like coronary artery disease, cerebro vascular diseases and the recommendation of greater routine evaluation of serum lipid profile, its treatment and good glycemic control in patients of type-2 diabetes mellitus is strongly suggested.