Preparation of New Perfluoroalkylated Carbamate Group-containing Glycoside-based Nonionic Surfactants
The present work describes the synthesis of new perfluoroalkylated carbamate group-containing glycoside-based nonionic surfactants usable as co-surfactants for stabilizing injectable oxygen-carriers PFC emulsions and as potential antithrombotic agents. The key steps of the synthetic route converting...
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Published in | Tenside Surfactants Detergents Vol. 44; no. 2; pp. 116 - 120 |
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Main Authors | , , , |
Format | Journal Article |
Language | English |
Published |
De Gruyter
01.04.2007
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Subjects | |
Online Access | Get full text |
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Summary: | The present work describes the synthesis of new perfluoroalkylated carbamate group-containing glycoside-based nonionic surfactants usable as co-surfactants for stabilizing injectable oxygen-carriers PFC emulsions and as potential antithrombotic agents. The key steps of the synthetic route converting F-alkyl oxoesters into new F-alkyl glycosides are: formolysis, conversion to the respective acid chloride, isocyanate formation and glycosidation. The perfluoroalkyl group is connected through a carbamate function to 6-position of the sugar ring, and the glycosidation is performed from unprotected sugar. |
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ISSN: | 0932-3414 2195-8564 |
DOI: | 10.3139/113.100333 |