A PRELIMINARY STUDY OF THE EFFECTIVENESS OF TECHNETIUM-99m-MIBI SCINTIGRAPHY IN BREAST TUMORS

We prospectively studied a total of 33 patients (5 benign, 28 malignant) with breast mass to evaluate the degree of accumulation of 99mTc-MIBI on scintigraphy. The axillary and breast lesions were evaluated in all patients. All patients had excisional biopsy or surgery after 99mTc-MIBI scintigraphy....

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Published inNihon Rinsho Geka Gakkai Zasshi (Journal of Japan Surgical Association) Vol. 61; no. 8; pp. 1965 - 1968
Main Authors HAYASHI, Tomohiko, SATO, Nariatsu, NAKAMOTO, Ai, YAGI, Haruo, TAKEDA, Toshiya, KOYASAKI, Naohiro, KAMATA, Toru, KANNO, Masahiro
Format Journal Article
LanguageEnglish
Published Japan Surgical Association 2000
Subjects
99mTc-MIBI SPECT
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Summary:We prospectively studied a total of 33 patients (5 benign, 28 malignant) with breast mass to evaluate the degree of accumulation of 99mTc-MIBI on scintigraphy. The axillary and breast lesions were evaluated in all patients. All patients had excisional biopsy or surgery after 99mTc-MIBI scintigraphy. The sensitivity of 99mTc-MIBI scintigraphy for malignant tumor was 96% (27/28), but specificity was 100% (5/5). The sensitivity for axillary lymph node metastasis was 58% (7/12), but specificity was 100% (14/14). Loss of 99mTc-MIBI uptake in lesions in delayed image which was considered to be due to wash out, was seen 14 of 39 lesions (36%) and was probably related to multidrug resistance. 99mTc-MIBI scintigraphy was able to diagnose this malignancy. This study showed that 99mTc-MIBI scintigraphy had a high diagnostic accuracy for the detection of primary breast cancer axillary lymph node metastasis.
ISSN:1345-2843
1882-5133
DOI:10.3919/jjsa.61.1965