A case of mandibular hemophilic pseudotumor

• Published in: Japanese Journal of Oral and Maxillofacial Surgery Vol. 46; no. 2; pp. 105 - 107
• Main Authors: SHIROZU, Takamasa, MIYACHI, Hitoshi, KAWAHARA, Kou, HOTTA, Fumio, TOHYA, Tousei
• Format: Journal Article
• Language: English
• Published: Japanese Society of Oral and Maxillofacial Surgeons 2000
• Subjects: hemophilia A; hemophilic pseudotumor; mandible
• ISSN: 0021-5163; 2186-1579
• DOI: 10.5794/jjoms.46.105

A hemophilic pseudotumor was found in the mandible a of a 13-year-old boy with a known history of moderate hemophilia A. Intraorally, the alveolus was enlarged buccally and lingually in the left retromolar region. Hypesthesia of the left mental region was noted. Panoramic X-ray film revealed a lytic bone lesion from 7 to the left angle of the mandible. Computed tomography revealed marked enlargement of the left side of the body of the mandible, associated with a low density area, and irregular absorption of the lingual cortex. A malignant tumor was suspected, so a biopsy was done during replacement therapy with coagulation factor (Factor VIII). The bone cavity contained a hematoma and was surrounded by granulation-like tissue. A histopathologic diagnosis of hemophilic pseudotumor was made. One year after curretage, the patient's condition was normal, both clinically and radiologically. The pathogenetic mechanism was hypothesized to be a pressure-necrosis phenomenon due to intraosseous bleeding.