EARLY EFFECT OF IRRADIATION AND HISTOLOGICAL SUB-TYPE OF CERVICAL CANCER OF UTERUS

In the cases of radiotherapy of cervical cancer of uterus, radiosensitivity of cancer tissue has an important influence on the prognosis and on the selection of the therapeutic method. For radiotherapist, it is very beneficial to interpret radiosensitivity before radiotherapy or on the early time of...

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Published inKita Kantō igaku (The Kitakanto Medical Journal) Vol. 30; no. 2; pp. 1 - 8
Main Author MURAKAMI, YUKO
Format Journal Article
LanguageEnglish
Published The Kitakanto Medical Society 1980
Subjects
Cervical Cancer
Early Effect of Irradiation
Histological Classification of Cervical Cancer
Radioresponse of Cervical Cancer
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Summary:In the cases of radiotherapy of cervical cancer of uterus, radiosensitivity of cancer tissue has an important influence on the prognosis and on the selection of the therapeutic method. For radiotherapist, it is very beneficial to interpret radiosensitivity before radiotherapy or on the early time of radiotherapy. We classified epidermoid carcinoma of cervix into three sub-types, each of which has respectively different radiosensitivity. Three sub-type s are as followed. Type I : Keratinizing type, high degree of Keratinization. Type II : Basal cell type, uniform proliferation of spindle cell. Type III : Intermediate type, intermediate disposition between keratinizing type and basal cell type. As to early time of irradiation, keratinizing type has low radiosensitivity, and basal cell type has high radiosensitivity. Intermediate type has middle radiosensitivity. Moreover early radiosensitivity correlate with prognosis. Early radiosensitivity could be manifest ed by histological changes observed 6 hours after 400 rad irradiation.
ISSN:0023-1908
1883-6135
DOI:10.2974/kmj1951.30.2_1