R ST Calc: a collection of computer programs for calculating estimates of genetic differentiation from microsatellite data and determining their significance
Abstract R ST , an analogue of F ST , provides a convenient approach for estimating levels of genetic differentiation from microsatellite data. This paper examines current approaches for calculating estimates of R ST and suggests a weighting scheme based on the transformation of allele sizes at loci...
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| Published in | Molecular ecology Vol. 6; no. 9; pp. 881 - 885 |
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| Main Author | |
| Format | Journal Article |
| Language | English |
| Published |
01.09.1997
|
| Online Access | Get full text |
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| Summary: | Abstract
R
ST
, an analogue of
F
ST
, provides a convenient approach for estimating levels of genetic differentiation from microsatellite data. This paper examines current approaches for calculating estimates of
R
ST
and suggests a weighting scheme based on the transformation of allele sizes at loci across data sets. Combined within an analysis of variance framework this scheme yields an estimator of
R
ST
analogous to the θ estimator of
F
ST
. Software for the IBM‐PC is described which carries out such calculations and assesses the significance of
R
ST
or
Nm
estimates using bootstrap and permutation tests. |
|---|---|
| ISSN: | 0962-1083 1365-294X |
| DOI: | 10.1111/j.1365-294X.1997.tb00143.x |