High Cardio-Ankle Vascular Index in Patients Who Have Coronary Spastic Angina

• Published in: Myakkangaku = The Journal of Japanese College of Angiology Vol. 52; no. January; pp. 41 - 45
• Main Authors: Kiuchi, Shunsuke, Kawasaki, Muneyasu, Hirashima, Osamu, Shintani, Yodo, Niitsu, Katsuji, Yamasaki, Junichi
• Format: Journal Article
• Language: Japanese
• Published: Japanese College of Angiology 2012
• Subjects: cardio ankle vascular index; coronary spastic angina; endothelial dysfunction
• ISSN: 0387-1126; 1880-8840
• DOI: 10.7133/jca.52.41

Objectives: One form of etiology in coronary spastic angina (CSA) is vascular endothelial cell dysfunction which causes vascular distensibility disorder. On the other hand, cardio-ankle vascular index (CAVI) is a new parameter of arterial stiffness. This study aims to reveal the relationship between CSA and CAVI. Methodology: The subjects included were 41 patients who received the induction examination of coronary spasm with angiography. We evaluated the CSA (S) Group and the normal (N) Group, and compared the two groups. The laboratory findings (lipid and glucose profile), blood pressure, smoking, age, sex, ankle-brachial index (ABI), and CAVI were analyzed. Results: CAVI in the S Group was significantly higher than in the N Group (S: 8.78±0.82, N: 7.73±1.04, P=0.004). There were no significant differences in the other analyzed findings. Conclusion: The study revealed that vascular endothelial dysfunction caused CSA and increased CAVI.