188 : Platelet-Rich Plasma in Patients with In-Vitro Fertilization

• Published in: Fertility & reproduction Vol. 5; no. 4; p. 361
• Main Authors: Regan, Louis, Yulinda, Dafi, Jovito, Axel, Siregar, Fahreza Akbar, Wiweko, Budi
• Format: Journal Article
• Language: English
• Published: World Scientific Publishing Company 01.12.2023; World Scientific Publishing
• Subjects: ORAL PRESENTATION: ART, Clinical
• ISSN: 2661-3182; 2661-3174
• DOI: 10.1142/S2661318223741656

Background and Aims: Successful embryo implantation requires the presence of a receptive endometrium, and unsuccessful implantation frequently results from a thin endometrial wall. A new approach of treating thin endometrium, platelet-rich plasma (PRP), has been shown to increase endometrial thickness, vascularity, and implantation rate. The aim of this study is to assess PRP’s efficacy as a treatment for infertile women undergoing in vitro fertilization and its benefit for ART. Method: This retrospective study data was implemented by collecting 26 infertile women who were sent to the Yasmin IVF Center at the Dr. Cipto Mangunkusumo General Hospital in Jakarta and had a history of unsuccessful implantation. Results: There were 26 patients who underwent IVF and received PRP infusion prior to FET. The clinical pregnancy rate in this study was 87,5% for women <35 years old and 47% for women >35 years old. The clinical pregnancy rate was determined by dividing the number of fetal poles with a heartbeat seen on the 6-week-old ultrasound by the overall number of transplanted embryos. Conclusions: Autologous PRP injections have shown a highly effective treatment for RIF and refractory thin endometrium.