A Convenient Synthesis of α-Hydrosyiminoacetonitriles from Aldoximes

Aromatic α-hydroxyiminoacetonitriles can be conveniently prepared by a facile one-pot procedure in high yields involving chlorination of the corresponding aldoximes with tert-butyl hypochlorite followed by reaction with alkali cyanide.

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Published inSynthetic communications Vol. 29; no. 22; pp. 3863 - 3868
Main Authors Ma, Jun-An, Ma, Zh-Hua, Ma, Hong-Min, Huang, Run-Qiu, Shao, Rui-Lian
Format Journal Article
LanguageEnglish
Published Taylor & Francis Group 01.11.1999
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Abstract Aromatic α-hydroxyiminoacetonitriles can be conveniently prepared by a facile one-pot procedure in high yields involving chlorination of the corresponding aldoximes with tert-butyl hypochlorite followed by reaction with alkali cyanide.
AbstractList Aromatic α-hydroxyiminoacetonitriles can be conveniently prepared by a facile one-pot procedure in high yields involving chlorination of the corresponding aldoximes with tert-butyl hypochlorite followed by reaction with alkali cyanide.
Author Huang, Run-Qiu
Ma, Jun-An
Shao, Rui-Lian
Ma, Zh-Hua
Ma, Hong-Min
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Cites_doi 10.1021/jo01068a034
10.1016/S0040-4039(00)99608-4
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10.1002/prac.19020660123
10.1246/bcsj.50.718
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Title A Convenient Synthesis of α-Hydrosyiminoacetonitriles from Aldoximes
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