A Convenient Synthesis of α-Hydrosyiminoacetonitriles from Aldoximes

Aromatic α-hydroxyiminoacetonitriles can be conveniently prepared by a facile one-pot procedure in high yields involving chlorination of the corresponding aldoximes with tert-butyl hypochlorite followed by reaction with alkali cyanide.

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Bibliographic Details
Published in	Synthetic communications Vol. 29; no. 22; pp. 3863 - 3868
Main Authors	Ma, Jun-An, Ma, Zh-Hua, Ma, Hong-Min, Huang, Run-Qiu, Shao, Rui-Lian
Format	Journal Article
Language	English
Published	Taylor & Francis Group 01.11.1999
Online Access	Get full text

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Summary:	Aromatic α-hydroxyiminoacetonitriles can be conveniently prepared by a facile one-pot procedure in high yields involving chlorination of the corresponding aldoximes with tert-butyl hypochlorite followed by reaction with alkali cyanide.
ISSN:	0039-7911 1532-2432
DOI:	10.1080/00397919908085906