Terahertz ATR sheds light on real-time exchange kinetics occurring through plasma membrane during photodynamic therapy

THz ATR spectroscopy provides, in a single measurement, the relative number of defects per membrane surface created by oxidative stress generated during photodynamic therapy (PDT), offering early, sensitive real-time information. THz spectroscopy is therefore a complementary technique to established...

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Bibliographic Details
Published inEPJ Web of conferences Vol. 287; p. 3010
Main Authors Lordon, B., Zheng, X., Mingotaud, A. F., Vicendo, P., Brival, R., Fourquaux, I., Gibot, L., Gallot, G.
Format Journal Article
LanguageEnglish
Published EDP Sciences 01.01.2023
Subjects
Biochemistry, Molecular Biology
Life Sciences
Molecular biology
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Summary:THz ATR spectroscopy provides, in a single measurement, the relative number of defects per membrane surface created by oxidative stress generated during photodynamic therapy (PDT), offering early, sensitive real-time information. THz spectroscopy is therefore a complementary technique to established (biological) assays and can be applied to any topic requiring the real-time examination of short-term plasma membrane permeabilization.
ISSN:2100-014X
2100-014X
DOI:10.1051/epjconf/202328703010