Comparison Between Dried Blood Spot and Plasma Bosentan Pharmacokinetics In Paediatric Patients With Pulmonary Arterial Hypertension

DBS can be considered as a valid alternative to the plasma method for the analysis of bosentan PK in children with pulmonary arterial hypertension. [...]DBS has the advantage of requiring a very low blood volume and the samples can be stored at room temperature.

Saved in:
Bibliographic Details
Published inClinical therapeutics Vol. 37; no. 8; p. e148
Main Authors Gehin, M, Globig, S, Sidharta, P.N, Kusic-Pajic, A, Dingemanse, J
Format Journal Article
LanguageEnglish
Published Bridgewater Elsevier Inc 01.08.2015
Elsevier Limited
Subjects
Confidence intervals
Hypertension
Internal Medicine
Medical Education
Plasma
Online AccessGet full text

Cover

More Information
Summary:DBS can be considered as a valid alternative to the plasma method for the analysis of bosentan PK in children with pulmonary arterial hypertension. [...]DBS has the advantage of requiring a very low blood volume and the samples can be stored at room temperature.
ISSN:0149-2918
1879-114X
DOI:10.1016/j.clinthera.2015.05.423