A case of primary peritoneal adenosquamous cell carcinoma

• Published in: Nihon Rinsho Geka Gakkai Zasshi (Journal of Japan Surgical Association) Vol. 73; no. 9; pp. 2409 - 2414
• Main Authors: YAMASHITA, Tatsuya, SUZUHIGASHI, Masaya, HIGASHIMOTO, Masashi, OGURA, Osamu
• Format: Journal Article
• Language: Japanese; English
• Published: Japan Surgical Association 2012
• Subjects: adenosquamous cell carcinoma; chemotherapy; primary peritoneal carcinoma
• ISSN: 1345-2843; 1882-5133
• DOI: 10.3919/jjsa.73.2409

A 55-year-old woman was admitted to our hospital with abdominal fullness. She presented with mild anemia and anorexia. Computed tomography (CT), magnetic resonance imaging (MRI) and positron emission tomography (PET) indicated tumors with ascites in abdominal cavity. To make a pathological diagnosis, laparoscopic surgery was performed. Intra-operative findings revealed a disseminated mass at the peritoneum, omentum and pelvic cavity, with bloody ascites. In immunohistochemical analysis of the resected specimens, tumor cells were stained with epithelial markers such as Keratin, epithelial membrane antigen, CA19-9, Calretinin, and CAM5.2. Furthermore, carcinoma cells stained with 34βE12 and CK5/6 were also observed. Histopathological findings by immunohistochemical analysis resulted in a diagnosis of primary peritoneal adenosquamous cell carcinoma. After the reductive surgery, the patient was treated with PTX and CBDCA, however, she died of uncontrolled pleural effusion and ascites at 273 days postoperative. Here, we described a rare case of primary peritoneal adenosquamous cell carcinoma.