Design and Characterization of an Antimicrobial Biocomposite for Wound Dressings

• Published in: Materials Vol. 17; no. 19; p. 4705
• Main Authors: Becerril-Serna, Leslie, Aguilar-Uscanga, Blanca Rosa, Flores-Soto, Mario, Solís-Pacheco, Josué Raymundo, Cisneros-López, Erick Omar
• Format: Journal Article
• Language: English
• Published: Basel MDPI AG 25.09.2024; MDPI
• Subjects: Antiinfectives and antibacterials; Antimicrobial agents; Biocompatibility; Biodegradation; Biomedical materials; Biopolymers; Composite materials; Cytotoxicity; E coli; Glycerol; Mechanical properties; Moisture absorption; Morphology; Public health; Recovery (Medical); Sodium; Sodium alginate; Staphylococcus infections; Tensile strength; Water absorption; Water vapor; Wound healing; United States > US; Mexico
• ISSN: 1996-1944; 1996-1944
• DOI: 10.3390/ma17194705

Skin wounds, due to their high vulnerability to infections, represent a significant public health issue. These wounds are not only disabling but also entail costly treatments and slow recovery. Consequently, it is crucial to implement new treatments based on bioactive and natural antimicrobial compounds utilizing fibers, polymers, hydrocolloids, and hydrogels to control potential infections and promote wound healing. This study aimed to develop a biocomposite with antimicrobial activity for the treatment of skin wounds, using sodium alginate, bamboo fiber, and a natural antimicrobial as ingredients. The physico-mechanical properties (Young’s modulus, tensile strength, elongation at break, moisture absorption, and water vapor permeability) and antimicrobial activity against Escherichia coli, Staphylococcus aureus, and Staphylococcus hominis were determined. The results demonstrated that the designed biocomposite possesses adequate physico-mechanical properties, such as flexibility, strength, and water absorption capacity, in addition to exhibiting antibacterial activity, making it suitable to be used as a dressing in wound treatment.