Severe clinical toxicity caused by 25I-NBOMe confirmed analytically using LC-MS-MS method

Rhabdomyolysis is a relatively rare, but potentially seriouscomplication of various diseases. Muscular injuryand resultant release of electrolytes, myoglobin andother enzymatic proteins e.g. creatine kinase (CK) intocirculation may result in multi-organ failure requiring anextensive treatment. Non-t...

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Bibliographic Details
Published inActa biochimica polonica
Main Authors Waldman, Wojciech, Kała, Maria, Lechowicz, Wojciech, Gil, Dominika, Anand, Jacek Sein
Format Journal Article
LanguageEnglish
Published 18.10.2018
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Summary:Rhabdomyolysis is a relatively rare, but potentially seriouscomplication of various diseases. Muscular injuryand resultant release of electrolytes, myoglobin andother enzymatic proteins e.g. creatine kinase (CK) intocirculation may result in multi-organ failure requiring anextensive treatment. Non-traumatic causes of rhabdomyolysis,like poisonings, appear to be much more frequentthan traumatic causes. We present the case of a patientwho developed exceptionally massive rhabdomyolysis,with CK up to 516 455 U/l, after ingestion of a relativelysmall dose of a novel psychoactive substance knownas “Alice in Wonderland”. Laboratory quantification wasperformed using a validated LC-MS/MS method in awhole blood sample.
ISSN:0001-527X
1734-154X
DOI:10.18388/abp.2018_2627