Histochemical demonstration of terminal deoxynucleotidyl transferase in leukemia

White blood cells from 22 patients with leukemia and lymphoma were studied for the presence of terminal deoxynucleotidyl transferase with a peroxidase-antiperoxidase method. The enzyme was detected in leukemic cells of 5 patients with acute lymphoblastic leukemia and 1 patient with chronic myelogeno...

Full description

Saved in:
Bibliographic Details
Published inBlood Vol. 58; no. 4; pp. 856 - 858
Main Authors Hecht, T, Forman, SJ, Winkler, US, Santos, S, Winkler, KJ, Carlson, F, Maslow, WC, Borer, WZ, Blume, KG
Format Journal Article
LanguageEnglish
Published 01.10.1981
Online AccessGet full text

Cover

More Information
Summary:White blood cells from 22 patients with leukemia and lymphoma were studied for the presence of terminal deoxynucleotidyl transferase with a peroxidase-antiperoxidase method. The enzyme was detected in leukemic cells of 5 patients with acute lymphoblastic leukemia and 1 patient with chronic myelogenous leukemia, whereas 16 patients with different forms of leukemia or lymphoma were negative for this enzyme. Comparative studies using a biochemical and an indirect immunofluorescence assay revealed complete concordance between these three methods.
ISSN:0006-4971
1528-0020
DOI:10.1182/blood.V58.4.856.bloodjournal584856