Acquired Hemophilia in an Elderly Patient with Non-Small Cell Lung Cancer: a Case Report

Acquired hemophilia A (AHA) is a rare autoimmune disease caused by autoantibodies against coagulation factor VIII and characterized by spontaneous hemorrhage in patients with no previous family or personal history of bleeding. We report here a case of AHA that occurred in the Department of Medicina...

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Bibliographic Details
Published inSN comprehensive clinical medicine Vol. 5; no. 1
Main Authors Dulcetti, Antonio, Bruscia, C., Malena, D. M., Benvenuto, R., Martocchia, A., Sentimentale, A., Tafaro, L., March, M. Rocchietti, Martelletti, P.
Format Journal Article
LanguageEnglish
Published Cham Springer International Publishing 23.11.2022
Subjects
Case Report
Medicine
Medicine & Public Health
Topical Collection on Medicine
Acquired hemophilia A
Case report
Paraneoplastic
Bleeding
Recombinant activated factor VII
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Summary:Acquired hemophilia A (AHA) is a rare autoimmune disease caused by autoantibodies against coagulation factor VIII and characterized by spontaneous hemorrhage in patients with no previous family or personal history of bleeding. We report here a case of AHA that occurred in the Department of Medicina D’Urgenza in Sant’Andrea Hospital in a patient with previous diagnosis of NSLC. The aim of this article is to allow a more comprehensive knowledge of AHA that both for the rarity and the poor literature is underdiagnosed; for all these reasons, it is important that different specialists, like emergency specialists, experts in internal medicine, hematologists, and oncologists, acquire a more complete knowledge of the clinical and laboratory features of this disease, allowing an early diagnosis crucial for the evolution of the coagulopathy.
ISSN:2523-8973
2523-8973
DOI:10.1007/s42399-022-01330-x