Isolation and Characterisation of Flavonoids (Rutin) from the Roots of Cadaba aphylla (Thunb) and Adenia glauca of Potential in Anti-Oxidant activity

Natural medicine is widely used to treat a variety of ailments. This work aims to isolate and characterise flavonoids from the roots of Cadaba aphylla and Adenia glauca. The compound was extracted using the Ultrasonicate Assisted Extraction (UAE), and Chromatographic methods including thin layer chr...

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Bibliographic Details
Published inOriental journal of chemistry Vol. 38; no. 6; pp. 1404 - 1413
Main Authors Immaculate, A. Anitha, Vimala, J. Rosaline, Takuwa, David T.
Format Journal Article
LanguageEnglish
Published Bhopal Oriental Scientific Publishing Company 30.12.2022
Subjects
Ammonia
Chromatography
Color
Column chromatography
Flavonoids
Free radicals
Ions
Mass spectra
Metabolites
NMR
Nuclear magnetic resonance
Oxidizing agents
Roots
Scavenging
Solvents
Thin layer chromatography
Botswana
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Summary:Natural medicine is widely used to treat a variety of ailments. This work aims to isolate and characterise flavonoids from the roots of Cadaba aphylla and Adenia glauca. The compound was extracted using the Ultrasonicate Assisted Extraction (UAE), and Chromatographic methods including thin layer chromatography (TLC) and column chromatography were then used to separate it. The isolated compound was then examined using UV-visible, FTIR, NMR (H1 & C13), and mass spectra (MS) followed by antioxidant evaluation. From the qualitative and spectral examination. The isolated component is identified as 3, 3', 4', 5, 7-pentahydroxy flavones-3-rutinoside, it is concluded (Rutin) and it also showed good free radical scavenging behaviour. Therefore, these plants can be used for therapeutic purpose.
ISSN:0970-020X
2231-5039
DOI:10.13005/ojc/380610