Hypothyroidism and cognition in the elderly

The consequences of hypothyroidism on cognition are long known since the description of dementia associated with hypothyroidism. Additional data from experimental studies support the impact of thyroid hormones on the central nervous system and cognition. Cognitive impairment in relation with hypothy...

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Published inGériatrie et psychologie neuropsychiatrie du vieillissement Vol. 9; no. 4; pp. 477 - 489
Main Authors Chavanne, Dominique, Constans, Thierry, Petit, Anne, Mondon, Karl, Hommet, Caroline
Format Journal Article
LanguageFrench
Published France 01.12.2011
Subjects
Adult
Age Factors
Aged
Aged, 80 and over
Animals
Brain - physiopathology
Cognitive Dysfunction - diagnosis
Cognitive Dysfunction - physiopathology
Cross-Sectional Studies
Dementia - diagnosis
Dementia - physiopathology
Female
Humans
Hypothyroidism - complications
Hypothyroidism - diagnosis
Hypothyroidism - physiopathology
Longitudinal Studies
Male
Middle Aged
Thyroid Hormones - blood
Young Adult
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Summary:The consequences of hypothyroidism on cognition are long known since the description of dementia associated with hypothyroidism. Additional data from experimental studies support the impact of thyroid hormones on the central nervous system and cognition. Cognitive impairment in relation with hypothyroidism (even sub clinical hypothyroidism) in elderly subjects involves memory, attention, and executive functions. Hypothyroidism may be associated with somatic, neurologic, psychiatric, social and environmental data. Cross-sectional and longitudinal studies are frequently heterogeneous but suggest a complex relationship between hypothyroidism and cognition.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
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ObjectType-Review-1
ISSN:2115-7863
DOI:10.1684/pnv.2011.0300