Pioglitazone attenuates alcohol-induced alveolar macrophage oxidative stress and dysfunction by up-regulating microRNA-92a/b

Alcohol abuse increases risk of respiratory infections through impaired lung immunity mediated by enhanced oxidative stress and alveolar macrophage (AM) phagocytic dysfunction.

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Bibliographic Details
Published inAlcohol (Fayetteville, N.Y.) Vol. 48; no. 7; p. 734
Main Authors Yeligar, S.M, Harris, F.L, Brown, L.A.S, Hart, C.M
Format Journal Article
LanguageEnglish
Published Philadelphia Elsevier Inc 01.11.2014
Elsevier Limited
Subjects
Alcohol
Ethanol
MicroRNAs
Oxidative stress
Psychiatry
Rodents
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Summary:Alcohol abuse increases risk of respiratory infections through impaired lung immunity mediated by enhanced oxidative stress and alveolar macrophage (AM) phagocytic dysfunction.
ISSN:0741-8329
1873-6823
DOI:10.1016/j.alcohol.2014.09.030