Advances of lncRNA in autoimmune diseases

Long non-coding RNA (lncRNA) is a newly identified non-coding RNA with various regulatory functions. Recent evidence has shown how lncRNA affect the disease development at different degrees. Studies on lncRNA have made great progress in the fields of cancer diseases and generative disorders. However...

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Bibliographic Details
Published inFrontiers in laboratory medicine Vol. 2; no. 2; pp. 79 - 82
Main Authors Wang, Jiajian, Wei, Feng, Zhou, Haizhou
Format Journal Article
LanguageEnglish
Published Elsevier B.V 01.06.2018
Subjects
Autoimmune diseases
Autoimmunity
Long non-coding RNA
Autoimmunity
Autoimmune diseases
Long non-coding RNA
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Summary:Long non-coding RNA (lncRNA) is a newly identified non-coding RNA with various regulatory functions. Recent evidence has shown how lncRNA affect the disease development at different degrees. Studies on lncRNA have made great progress in the fields of cancer diseases and generative disorders. However, the autoimmune diseases is a relatively new research area. An increasing number of studies have stated in recent years that IncRNA plays a role in the protein transport & trafficking, gene transcription and other biological processes. This review focused on the advances of lncRNA in autoimmune diseases, such as systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), psoriasis, autoimmune thyroid disease (AITD), Sjogren's syndrome (SS) and Crohn's disease (CD).
ISSN:2542-3649
2542-3649
DOI:10.1016/j.flm.2018.07.004