Alcohol exposure dysregulates hematopoietic progenitor cell notch-mediated dendropoiesis

Additional studies are needed to assess the effect of alcohol on mDC2 differentiation because of this phenotype's ability to polarize T cells to a TH2 phenotype, a cell type correlated to enhanced human immunodeficiency virus (HIV) disease progression (Supported by NIH AA020312, AA009803, AA210...

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Bibliographic Details
Published inAlcohol (Fayetteville, N.Y.) Vol. 47; no. 7; p. 575
Main Authors Upchurch, G.M, Siggins, R.W
Format Journal Article
LanguageEnglish
Published Philadelphia Elsevier Inc 01.11.2013
Elsevier Limited
Subjects
Genotype & phenotype
HIV
Human immunodeficiency virus
Ligands
Psychiatry
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Summary:Additional studies are needed to assess the effect of alcohol on mDC2 differentiation because of this phenotype's ability to polarize T cells to a TH2 phenotype, a cell type correlated to enhanced human immunodeficiency virus (HIV) disease progression (Supported by NIH AA020312, AA009803, AA21097).
ISSN:0741-8329
1873-6823
DOI:10.1016/j.alcohol.2013.09.036