Anacardic acid derivatives from Brazilian propolis and their antibacterial activity
Propolis is a sticky, gummy, resinous substance collected by honeybees (Apis mellifera L.) from various plant sources, which has excellent medicinal properties. This paper describes the isolation and identification of triterpenoids and anacardic acid derivatives from Brazilian propolis and their ant...
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Published in | Eclética química Vol. 33; no. 3; pp. 53 - 58 |
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Main Authors | , , , , , , |
Format | Journal Article |
Language | English |
Published |
Universidade Estadual Paulista
01.04.2018
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Online Access | Get full text |
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Summary: | Propolis is a sticky, gummy, resinous substance collected by honeybees (Apis mellifera L.) from various plant sources, which has excellent medicinal properties. This paper describes the isolation and identification of triterpenoids and anacardic acid derivatives from Brazilian propolis and their antibacterial activity. Their structures were elucidated by 1H and 13C NMR, including uni- and bidimensional techniques; in addition, comparisons were made with data from academic literature. These compounds were identified as: cardanols (1a + 1b), cardols (2a + 2b), monoene anacardic acid (3), α-amirine (4), β-amirine (5), cycloartenol (6), 24-methylene-cycloartenol (7) and lupeol (8). The determination of the position of the double bond after a reaction with Dimethyl disulfide (DMDS) isdescribed for the phenol derivatives. The ethanolic extract was tested in vitro for antimicrobial activity by using the disc diffusion method and it showed significant results against Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa and Shigella spp. |
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ISSN: | 1678-4618 1678-4618 |
DOI: | 10.26850/1678-4618eqj.v33.3.2008.p53-58 |